Abstract:
Abstract
Background: Poor glycemic control is a main public health problem among type2 diabetes
mellitus patients and it leads to diabetic complications. In Ethiopia determination for predictors
of poor glycemic control level using glycosylated hemoglobin is not studied. Therefore, this
study was aimed to assess predictors of poor glycemic control and its correlation with albumin to
creatinine ratio using glycosylated hemoglobin. Objective: To assess factors of poor glycemic control and its correlation with albumin to
creatinine ratio among type 2 diabetes mellitus patients at University of Gondar compressive
specialized Referral Hospital North west Ethiopia, 2023. Method: Institutional based cross-sectional study was conducted from 01, April - 30, May /2023. This study includes 200 type 2 diabetes mellitus patients by using systematic random sampling
technique among type 2 diabetes mellitus patients who have follow up at the Hospital. To
measure glycosylated hemoglobin levels, serum creatinine and blood urea nitrogen, 5 ml of
Blood samples were collected in early morning. Data entry and analysis were performed using
SPSS version 26. Bivariate logistic regression analysis was used. Pearson’s correlation test was
done to test correlation of poor glycemic control with albumin creatinine ratio (P=0.002). Result: The prevalence of poor glycemic control was 82.5%. The predictors significantly
associated with poor glycemic control at 95% CI were being female (AOR=3.74, 95% CI
1.1,12.83), age >60 years (AOR 88.1, 95% CI 6.48,1197.2), BMI>25 (AOR 7.1, 95% CI
1.37,36.7), duration of diabetes (> 5 years) (AOR 4.35, 95% CI 1.1, 16.9) and anti-diabetic
medication (Insulin alone) (AOR 8.39, 95%CI 1.3,56.9). There was significant positive
correlation of HbA1c with ACR with (r=0.218, P value =0.002). Conclusion: Prevalence of poor glycemic control in type2 diabetes mellitus patients found to be
high. Being female, age, overweight, duration of diabetes, antidiabetic medication (insulin alone)
significantly associated with poor glycemic control. HbA1c significantly correlate with albumin
creatinine ratio. We recommended to those hospital health workers Effective educational and
therapeutic approach should be focused controlling body weight particularly on female patients.
