Abstract:
Abstract
Introduction:Drug interaction
Objectives: The aim of the study was to assess potential drug interactions, associated factors
and potential risks of major potential drug interactions in patients visiting the chronic outpatient
department
(
Methods: A hospital based cross-sectional study was conducted at UoGCSH from June 03 to
July 05, 2019. Data were collected from interview,prescription and patient chart review. Then
data were entered and analyzed using SPSS version 20. Binary logistic regression analysis was
done. A P-value<0.05 at 95% CI of the multivariable analysis was considered significant.
Results: A total of 403 study participants were included in the analysis. The prevalence of
potential drug-drug interaction
Conclusion and recommendations: Prevalence of pDDI and pDDisI were high compared
to most studies. Factors associated with them were: pDDI and pDDisI associated each other,
number of drugs per patient, type of drug and disease as well as comorbidity
Keywords: drug-drug interaction, drug-disease interaction, Gondar, Ethiopia
