Assessment of the magnitude, economic impact, and factors associated with expired veterinary pharmaceuticals in animal health facilities in South Wollo, Ethiopia

Abstract

Background: The issue of veterinary pharmaceutical expiration is a significant concern in animal health facilities globally. The existence of veterinary pharmaceutical expiration can be mainly associated with inadequate inventory control, store management, and a lack of effective pharmaceutical regulatory policies and guidelines. Hence, the study aimed to evaluate expired veterinary pharmaceuticals’ scope, economic impact, and contributing factors. Methods: A cross-sectional, explanatory sequential study design involving a mixed quantitative and qualitative approach was employed among 13 animal health facilities from March 2022 to December 2023 in and around Dessie town, South Wollo, Ethiopia. A key informant interview guide was used to retrieve the qualitative data that were analyzed through thematic content analysis. Then, the collected data were coded and analyzed using SPSS version 25. A mean score was used to determine the critical factors associated with veterinary pharmaceutical expiration. Results: The study found that the magnitude of expired veterinary pharmaceuticals in the fourth fiscal year was 7%. This wastage rate of veterinary pharmaceuticals led to a loss of approximately 69,564.54 USD. From expired veterinary pharmaceutical unit pack perspectives, approximately 403-unit packs (66%) expired in veterinary clinics, resulting in a loss of approximately 38,229.33 USD, and 209-unit packs (34%) expired in private veterinary pharmacies, incurring a loss of approximately 31,335.22 USD. From Anatomical Therapeutic Classification (ATC), antibiotics accounted for 14.8% of the total financial loss. Additionally, approximately 53% of liquid dosage for